In recent years there’s been a lot of buzz about a so-called “Botox in a bottle.” If you’re anything like me you’ve wondered— are these creams for real or is this just a lot of hype?
Good news! There is some data to the support the notion that needle-free Botox™ alternatives do work. There are new topical anti-aging peptides that are getting some very exciting results for fine lines.
Botox™ has been used successfully for 25 years to soften the appearance of wrinkles and frown lines. However, Botox can be on the expensive side, and some people may be averse to receiving injections. The new topical alternatives to Botox™ claim to block the communication between facial muscles and the nerves that tell these muscles to contract. Argireline® is probably the Botox™ alternative with the most evidence to date supporting its use in anti-wrinkle serums. Argireline®, also known as hexapeptide-6, is a small protein that claims to result in relaxed facial muscle activity by inhibiting the release of acetylcholine, the neurotransmitter that is responsible for facial muscle activity. Studies looking at Argireline® have demonstrated a reduction in wrinkle depth of up to 60 percent after one month of use. Look for anti-aging formulations with at least 10 percent Argireline® for optimal reduction of fine lines. The results you will see with these creams and serums are far less dramatic than any injectable can promise, and they take a little longer to appear. But I am happy to report that “Botox in a bottle” is more than just hype; it’s good science!